Academics

Brianna Harfmann

Title

Assistant Professor

Discipline

Integrative Physiology and Health Science

Educational Background

Education and work experience

  • B.S. Exercise and Health Science, Alma College, 2007-2011.
  • Ph.D. Physiology, University of Kentucky, 2011-2015.
  • Postdoctoral fellow, University of Kentucky, 2015-2017.
  • Adjunct Professor of Biology, Bluegrass Community and Technical College, 2015-2017.
  • Adjunct Professor of Biology, Transylvania University, 2016-2017.

Rank

Assistant Professor

My career at Alma began in

2017

I'm an expert in

circadian rhythms and skeletal muscle glucose metabolism.

My expertise:

My areas of interest include circadian rhythms and metabolism. My primary research investigates the role of the circadian clock in regulating skeletal muscle metabolism.

Signature course(s):

IPH 225 - Physiology I, IPH 401 - Molecular Aspects of Muscle Physiology

Recent publications:

  • Finlin, BS, Memetimin, H, Confides, AL, Kasza, I, Zhu, B., Vekaria, HJ, Harfmann, BD, Jones, KA, Johnson, ZR, Westgate, PM, Alexander, CM, Sullivan, PG, Dupont-Versteegden, EE, Kern, PA. Human adipose beiging in response to cold and mirabegron. JCI insight 3, 15 (2018).
  • Finlin, BS, Zhu, B., Confides, AL, Westgate, PM, Harfmann, BD , Dupont-Versteegden, EE, Kern, PA. Mast Cells Promote Seasonal White Adipose Beiging in Humans. Diabetes 66, 5 (2017): 1237-1246. 
  • Seward T, Harfmann BD, Esser KA and Schroder EA. Reinventing the wheel: Comparison of two wheel cage styles for assessing mouse voluntary running activity. J Appl Phys, 2017.
  • Harfmann BD, England JH, Senn NJ, Schroder EA, Esser KA and Kern PA. Temperature as a circadian marker in older human subjects: relationship to metabolic syndrome and diabetes. J Endocr Soc, 2017.
  • Finlin B, Zhu B, Confides A, Harfmann B, Dupont-Versteegden E, Kern PA. Mast cells promote seasonal white adipose beiging in humans. Diabetes, 2017.
  • Harfmann BD, Schroder EA, Zhang X and Esser KA. Muscle specific loss of Bmal1 leads to disrupted tissue glucose metabolism and systemic glucose homeostasis. Skelet Muscle, 2016.
  • Schroder EA, Harfmann BD, Zhang X, Srikuea R, England JH, Hodge BA, Wen Y, Riley LA, Yu Qi, Christy AD, Smith JD, Wolf Horrell EM, Mula J, Peterson CA, Butterfield TA and Esser KA. Intrinsic muscle clock is necessary for musculoskeletal health. J Physiol, 2015.
  • Hodge BA, Wen Y, Riley LA, Zhang X, England JH, Harfmann BD, Schroder EA and Esser KA. The endogenous molecular clock orchestrates the temporal separation of substrate metabolism in skeletal muscle. Skelet Muscle, 2015.
  • Harfmann BD, Schroder EA and Esser KA. Circadian rhythms, molecular clock and skeletal muscle. Invited review. J Biol Rhythms, 2014.

Recent presentations:

Abstracts

  • Harfmann BD, Schroder EA, Zhang X, Esser KA. 2014. Impaired glucose homeostasis following loss of skeletal muscle Bmal1. Poster Presentation - ACSM Conference on Integrative Physiology of Exercise.
  • Harfmann BD, Schroder EA, Zhang X, Esser KA. 2014. Impaired glucose homeostasis following loss of skeletal muscle Bmal1. Poster Presentation – Cell Symposia.
  • Harfmann BD, Schroder EA, Zhang X, Esser KA. 2014. Development of metabolic disease following disruption of skeletal muscle circadian rhythms. Poster Presentation – Barnstable Brown Obesity and Diabetes Research Day.
  • Harfmann BD, Esser KA. 2013. Disruption of skeletal muscle circadian rhythms leads to altered metabolism.
    Poster Presentation – Center for Muscle Biology, Lexington, Kentucky
  • Harfmann BD, Esser KA. 2013. Loss of skeletal muscle circadian rhythms leads to altered metabolism.
    Oral Presentation – Gill Heart Institute Cardiovascular Research Day, Lexington, Kentucky
  • Harfmann, Hodge BA, England JH, Schroder EA, Esser KA. 2013. Skeletal muscle specific loss of Bmal1 leads to accelerated aging.
    Poster Presentation – Circadian Summer School, Nashville, Tennessee
  • Harfmann BD, Srikuea R, Esser KA. 2012. Loss of Bmal1 leads to accelerated aging of skeletal muscle.
    Poster Presentation – Center for Muscle Biology, Lexington, Kentucky
  • Harfmann BD, Hernandez MK, Ball KL. 2010. IGF-I protects against statin myotoxicity.
    Poster Presentation – ACSM Annual Conference, Denver, Colorado