Academics

Jeffrey Turk

Title

Associate Professor

Discipline

Chemistry

Educational Background

  • Postdoctorate, Purdue University (2002-2004)
  • Ph.D., University of Cincinnati (2002)
  • M.S., University of Cincinnati (2001)
  • B.S., Cleveland State University (1997)

Rank

Associate Professor

My career at Alma began in

2006

I'm an expert in

Organic, Medicinal and Flavor and Fragrance Chemistry

Signature course(s):

Introductory Organic Chemistry (CHM 223/224), Advanced Organic Chemistry (CHM 411), Medicinal Chemistry (CHM 310), Flavor and Fragrance Chemistry (CHM 312)

Recent publications:

  • Turk, J. A.; Beckman, J. D.  “Resources for an Investigative and Sustainable Undergraduate Medicinal Chemistry Program”  J. Chem. Educ., 2012, 90, 137-139.
  • Shubert, V. A.; Baquero, E. E.; Clarkson, J. R.; James, W. H. III; Turk, J. A.; Hare, A. A.; Morrel, K.; Lipton, M. A.; Schofield, D. P.; Jordan, K. D.; Zwier, T. S.  Entropy-driven population distributions in a prototypical molecule with two flexible side chains: O-(2-acetamidoethyl)-N-acetyltyramine.  J. Chem. Phys., 2007, 127, 234315. (I directed Alissa’s synthesis projects during my postdoctoral appointment at Purdue University.  Alissa was then in High School)
  • Krishnamoorthy, R.; Vazquez-Serrano, L. D.; Turk, J. A.; Kowalski, J. A.; Benson, A. G.; Breaux, N. T.; Lipton, M. A.  Solid-Phase Total Synthesis and Structure Proof of Callipeltin B.  J. Am. Chem. Soc., 2006, 128, 15392-15393.
  • Turk, J. A.; Visbal, G.; Lipton, M. A.  Asymmetric Synthesis of Four Diastereomers of 3-Hydroxy-2,4,6-Trimethylheptanoic acid:  Proof of Configurational Assignment.  J. Org. Chem., 2003, 68, 7841-7844.
  • Turk, J. A.; Smithrud, D.B.  Synthesis and Evaluation of Peptidomimetics that Bind DNA. Bioorg. Med. Chem., 2003, 11, 2355-2366.
  • Turk, J. A.; Smithrud, D.B.  Synthesis and Physical Properties of Protein Core Mimetics.  J. Org. Chem., 2001, 66, 8328-8335.
  • Duan, S.; Turk, J.; Spiegle, J.; Corbin, J.; Masnovi, J.; Baker, R. J.  Halogenations of Anthracenes and Dibenz[a,c]anthracene with N-Bromosuccinimide and N-Chlorosuccinimide.  J. Org. Chem., 2000, 65, 3005-3009.

 

Recent presentations:

  • “Design, Synthesis and Testing of Group-1 Specific Neuraminidase Inhibitors.” 244th ACS National Meeting; Philadelphia, PA. 2012. (oral)

  • “Group-1 Specific Neuraminidase Inhibitors Containing an Aromatic Scaffold” Cuthbertson, C. R.; Hanisko, J. M.; Kravat, A. J.; Turk, J. A.   244th ACS National Meeting; Philadelphia, PA. 2012. (poster)
  • “Di- and Tri-Substituted Aromatic Inhibitors of N1 Neuraminidase”, Monroe, A. J.; Gaudard, C. J.; Martinez, C.; Somers, B.; Turk, J. A. 

          American Chemical Society, Midland Section (Alma, MI), October 2011. (oral)

          American Chemical Society, Midland Section (Alma, MI), October 2011. (poster)

  • “Neuraminidase, Transfections and Neuraminidase Inhibitors.”, Campbell, J.; Turk, J. A.; Beckmann, J. D.  PRISM Summer Research Symposium, Alma College, August 2011. (oral)
  • “Developing Recombinant N1 Neuraminidase”, Armstrong, R.; Turk, J. A.; Beckmann, J. D.  

          American Chemical Society, Midland Section (Alma, MI), October 2011, (oral) 

          Honor’s Day, Alma College, April 2011. (oral)

  • “Design, Synthesis and Evaluation of Group-1 Specific Neuraminidase Inhibitors”, Monroe, A. J.; Somers, B.; Turk, J. A.  Student Summer Research Symposium, Alma College, October 2010. (oral)
  • “Engineering the N1 Gene for Viral Neuraminidase Expression”, Armstrong, R.; Duymich, C.; Turk, J. A.; Beckmann, J. D. West Michigan Regional Undergraduate Science Research Conference (Grand Rapids, MI), October 2010. (poster)
  • “Design, Synthesis and Evaluation of Group-1 Specific Neuraminidase Inhibitors”, Duymich, C.; Kallgren, J.; Turk, J. A.  

          Honor’s Day, Alma College, April 2009. (oral) Shared winners of Kapp prize.

          American Chemical Society Meeting (Midland, MI), October 2008. (poster)

  • “Sandalwoods via the Allene-Claisen Rearrangement”, Reed, B.; Turk, J. A.  American Chemical Society Meeting (Midland, MI), October 2008. (poster)  Winner of Best Undergraduate Poster. 
  • “Synthesis and Evaluation of Group-1 Neuraminidase Inhibitors”, Duymich, C.; Turk, J. A.  Student Summer Research Symposium, Alma College, September 2008. (oral)
  • “Sandalwoods via the Allene-Claisen Rearrangement”, Reed, B.; Turk, J. A. Student Summer Research Symposium, Alma College, September 2008. (oral)
  • “Characterization of Trinitrophenylated Adenosine Nucleotide Binding to Bovine Phenol Sulfotransferase (bSULT1A1).”  Macdonald, J.A.; Sawin, A.; Lapham, D.; White, J.; Turk, J.A.; Beckmann, J.D. FASEB/American Society of Biochemistry and Molecular Biochemistry, 2008. (poster, collaboration with Dr. Beckmann)

 

Recent grants:

  • National Science Foundation ($150,000, funded 2009-2013)

    Title: “RUI: Design, Synthesis and Evaluation of Group-1 Specific Neuraminidase Inhibitors”

  • Grant initiative program ($5000, funded 2011) 

    Title:  “Synthesis of Sandalwood Odorants via Allene-Claisen Rearragements”

  • Faculty Travel Award ($600, funded 2009) 

    Awarded by ACS National Organic Symposium for travel to NOS (2009, Boulder, CO)

  • Grant initiative program ($5000, funded 2007) 

    Title:  “Inhibition of the Avian Influenza Virus Neuraminidase (N1)”

  • Faculty small grants (funded)

    Acquisition of solid phase microextraction (SPME) materials for research and incorporation into teaching ($600, 2010)

    In support of enzyme inhibitor project ($215, 2009)

    In support of fragrance ingredient synthesis projects ($450 each, 2006, 2007, 2008)